Lipoprotein(a) is a largely genetically determined lipoprotein associated with cardiovascular risk factors. A single measurement gives insight into your Lp(a) level.
Interpreted by BIG-registered doctors
Achtergrond
Lipoprotein(a), abbreviated Lp(a), is a lipoprotein that shares structural similarities with LDL cholesterol, but also contains a unique protein (apolipoprotein(a)). The level is largely genetically determined and remains relatively stable for most people throughout their lifetime, lifestyle, diet, and most cholesterol medications have little influence on it.
Lp(a) is associated with an increased risk of cardiovascular disease and is increasingly recognised internationally as an additional cardiovascular risk marker, alongside the standard cholesterol profile. Because the level is stable, Lp(a) is typically measured once only, a repeat measurement is usually not necessary.
In het kort
Lipoprotein
Related to LDL cholesterol
Genetically determined
Largely by heredity
Stable for life
A single measurement usually suffices
Cardiovascular
Additional risk marker
Veelvoorkomende redenen om te meten
Hieronder enkele situaties waarin een meting van Lp(a) inzicht kan bieden.
A single measurement gives insight into this largely genetically determined marker.
Cardiovascular disease at a young age in the family is an important reason to have Lp(a) tested.
For those who want a broader picture of their cardiovascular risk factors, Lp(a) is a logical addition to the standard cholesterol profile.
Because Lp(a) is largely genetically determined and stable throughout life, this measurement is generally not repeated.
People who have themselves experienced a cardiovascular event often also want to know their Lp(a) level.
In a comprehensive heart and vascular package, Lp(a) is often included alongside ApoB.
Wat betekent uw uitslag
Lp(a) is measured in nanomoles per litre (nmol/L) or milligrams per decilitre (mg/dL). Our doctor interprets your value against the standard thresholds for cardiovascular risk assessment.
A low Lp(a) level gives a reassuring picture for this specific risk factor. This says nothing about your other cardiovascular risk factors, those remain important to monitor. Re-testing is usually not worthwhile as Lp(a) is largely genetically fixed.
A mildly elevated Lp(a) level is associated with a moderately increased risk element. The approach is usually extra vigilance regarding other modifiable cardiovascular factors. Our doctor provides explanation and context.
Significantly elevated Lp(a) is associated with increased cardiovascular risk. Since Lp(a) itself cannot easily be modified, the focus is on optimising all other modifiable cardiovascular factors. Our doctor provides explanation and recommends discussing this with your GP.
Hoe wij uw uitslag interpreteren
Our doctors interpret your Lp(a) in the context of your other cardiovascular risk factors, age, family history, cholesterol, blood pressure, BMI, smoking status. You receive a report in plain language, as a starting point for your own insight or a conversation with your healthcare provider.
Related tests
A single marker gives one perspective. For a broader picture you can combine Lp(a) with a theme package or related markers.
Veelgestelde vragen
No, you do not need to fast for an Lp(a) measurement.
Lp(a) is largely genetically determined and stable throughout life. A single measurement suffices in virtually all cases, repeat testing is usually of no added value.
Diet, exercise, and weight changes have little effect on Lp(a). Most cholesterol medications also do not lower Lp(a), or barely so. However, new medications specifically targeting Lp(a) are in development.
LDL cholesterol is the well-known "bad" cholesterol. Lp(a) resembles LDL in structure but contains a unique additional protein (apolipoprotein(a)). Lp(a) is an independent risk marker, even with normal LDL, Lp(a) can be elevated.
It is estimated that 1 in 5 people have elevated Lp(a). The distribution is largely genetically determined and differs between population groups.
For elevated values, our doctors advise discussing this with your GP in the context of comprehensive cardiovascular risk management, with a focus on other modifiable factors.
You will receive a PDF report with your value and explanation. What you do with it, such as discussing it with your GP or cardiologist, remains entirely your choice.
Yes, the report is written in medical language and contains all relevant laboratory information.
In the Health Guide
For €79 you receive your Lp(a) level including personal explanation from a doctor, typically within 2 business days. No referral required.
Order Lp(a) for €79 →Want to test multiple markers at once?
Combine Lp(a) with other markers via Bloodworks Select. Blood draw costs are waived from €225.
Customer service
Available on weekdays from 9:00 – 17:00
