PSA (Prostate-Specific Antigen) is a protein produced by the prostate. The level provides information about the prostate and is often measured as part of prostate monitoring.
Interpreted by BIG-registered doctors
Achtergrond
PSA stands for Prostate-Specific Antigen, a protein produced by the prostate gland that enters the blood in small amounts. PSA is "prostate-specific" in that it is produced exclusively by prostate tissue, but it is not a specific marker for any one particular condition.
The PSA level can be elevated for various reasons, not only prostate cancer, but also benign prostatic hyperplasia (BPH), prostatitis, a recent cycle ride, ejaculation within 48 hours, or a digital rectal examination. Reference values are age-dependent: what is normal for a 70-year-old may be elevated for a 40-year-old. PSA is a standard measurement within the framework of NHG guidelines relating to prostate monitoring.
In het kort
Prostate protein
Produced in the prostate gland
Age-dependent
Different reference range per age
Non-specific
Elevation has multiple causes
NHG-compliant
Part of the prostate guideline
Veelvoorkomende redenen om te meten
Hieronder enkele situaties waarin een meting van PSA inzicht kan bieden.
A test gives a baseline or follow-up measurement of your PSA level.
From the age of 50–55, PSA is more commonly measured as part of prostate monitoring; with a family history, earlier testing is considered.
Prostate cancer runs in families. With a family history, PSA monitoring can begin at an earlier age.
Those who have previously had an elevated or borderline value can use a repeat measurement to track the trend.
Men wishing to monitor their health periodically include PSA as part of a broader check.
Some men measure PSA following discussion with their GP or urologist as part of an agreed monitoring plan.
Wat betekent uw uitslag
PSA is measured in nanograms per millilitre (ng/mL). Reference values are age-dependent. Our doctor interprets your value against the age-specific guideline and your personal context.
A low PSA level gives a reassuring picture for this moment. Periodic re-testing can be worthwhile as part of general health monitoring from middle age onwards, particularly with a family history.
A PSA within the age-adjusted reference range is reassuring. For a relative increase within the normal range, such as a rapid rise between measurements, vigilance is appropriate. Our doctor provides explanation and context.
An elevated PSA warrants further investigation, but does not automatically mean prostate cancer is present. Many benign factors can raise PSA. For elevated values, our doctor provides explanation and context, so you can discuss this with your GP for further evaluation.
Hoe wij uw uitslag interpreteren
Our doctors interpret your PSA against the age-adjusted reference ranges and your personal context, including previous PSA values where available (trend), family history, and recent activities that can temporarily raise PSA.
Related tests
A single marker gives one perspective. For a broader picture you can combine PSA with a theme package or related markers.
Veelgestelde vragen
No, you do not need to fast for a PSA measurement.
Various factors can temporarily raise PSA, including a cycle ride shortly before the measurement, ejaculation within 48 hours, a recent digital rectal examination, or prostatitis. For a reliable measurement, it is advisable to avoid sexual activity and intensive cycling for 48 hours beforehand.
In the Netherlands, PSA is not routinely measured in a population screening programme. Many men consider testing from the age of 50–55, and earlier with a family history. It is a personal decision which you can discuss with your GP.
Total PSA measures all PSA in the blood. Free PSA measures the unbound fraction. The ratio between the two can provide additional information in specific situations, often in consultation with a urologist.
For a single measurement for insight, once is sufficient. For follow-up or monitoring, annual or biennial testing is common, depending on age, previous values, and family history.
For elevated values, our doctor provides explanation and advises discussing this with your GP for further evaluation. This typically begins with a repeat measurement and possibly a digital rectal examination.
You will receive a PDF report with your value and explanation. What you do with it, such as discussing it with your GP, remains entirely your choice.
Yes, the report is written in medical language and contains all relevant laboratory information. Many men bring it to their GP.
For €69 you receive your PSA level including personal explanation from a doctor, typically within 2 business days. No referral required.
Order PSA for €69 →Want to test multiple markers at once?
Combine PSA with other markers via Bloodworks Select. Blood draw costs are waived from €225.
Customer service
Available on weekdays from 9:00 – 17:00
